腺病毒载体的研究进展
范凌云,谢庆军
摘要(Abstract):
目的由于腺病毒载体转导目的基因具有高效率、低致病性、高滴度以及在体内不整合入宿主细胞染色体等优点,已被认为是最有效的转基因载体之一,并广泛应用于人类基因治疗。但是腺病毒载体还存在一些不足,如具有一定的免疫原性和毒性等,尚有待进一步解决。随着腺病毒载体研究的进展,新的载体系统必将在基因治疗中发挥更重要的作用。本文对腺病毒载体的研究进展作一综述。
关键词(KeyWords):
腺病毒;载体;基因治疗
基金项目(Foundation):
作者(Author):
范凌云,谢庆军
DOI: 10.13200/j.cjb.2008.02.78.fanly.004
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